Calcium and ROS-mediated activation of transcription factors and TNF- cytokine gene expression in macrophages exposed to ultrafine particles
نویسندگان
چکیده
D. M. Brown, K. Donaldson, P. J. Borm, R. P. Schins, M. Dehnhardt, P. Gilmour, L. A. Jimenez, and V. Stone School of Life Sciences, Napier University, and ELEGI Laboratory, University of Edinburgh, Edinburgh, United Kingdom; Particle Research Core, Institut für Umweltmedizinische Forschung, Düsseldorf, Germany; and Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, North Carolina
منابع مشابه
Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles.
Ultrafine (Uf) particles are a component of particulate air pollution suggested to be responsible for the health effects associated with elevations of this pollutant. We have previously suggested that Uf particles, through the induction of oxidative stress, may induce inflammation in the lung, thus exacerbating preexisting illness in susceptible individuals. Alveolar macrophages are considered ...
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تاریخ انتشار 2003